LDL Calculated

id

70

full_title

LDL Calculated

short_title

LDL Calculated

med_description

Calculates LDL based on total and HDL cholesterol and triglycerides.

description

The LDL Calculated calculates LDL based on total and HDL cholesterol and triglycerides.

keywords

LDL Calculated, LDL, HDL, triglycerides, ldl calc, ldl calculator, ldl calc online, ldl online, ldl, hdl, triglycerides calc, hdl calc, cholesterol calc, cholesterol average, low-density lipoprotein calc, low-density lipoprotein average, low-density lipoprotein calculator, low-density lipoprotein score, low-density lipoprotein scale, low-density lipoprotein issue, low-density lipoprotein cholesterol, bad cholesterol level, bad cholesterol calculator, bad cholesterol calculated, ldl based on hdl, ldl based on triglycerides, ldl from hdl, ldl from tryglycerides, ldl level, ldl risk, ldl risk factors, ldl smoking, ldl cigarettes, ldl DM, ldl diabetes, ldl htn, ldl hypertension, ldl high bp, ldl blood pressure, ldl family history, ldl hx, ldl family hx

complaint

[ "Chest Pain", "Preventive Care/Screening" ]

formula

LDL cholesterol, mg/dL = (total cholesterol, mg/dL) - (HDL, mg/dL) - [(triglycerides, mg/dL)/5]

evidence

measurements

[ { "name": "Total Cholesterol", "unit": "chol_total", "error_min": "40", "error_max": "1000", "warn_min": "150", "warn_max": "500", "conversion": "0.02586", "normal_max_si": "5.2", "normal_max_us": "200", "normal_min_si": "3.9", "normal_min_us": "150", "units_si": "mmol/L", "units_us": "mg/dL" }, { "name": "Triglycerides", "unit": "trig", "error_min": "0", "error_max": "400", "warn_min": "0", "warn_max": "300", "conversion": "0.0113", "normal_max_si": "1.7", "normal_max_us": "150", "normal_min_si": "0", "normal_min_us": "0", "units_si": "mmol/L", "units_us": "mg/dL" }, { "name": "HDL Cholesterol", "unit": "chol_hdl", "error_min": "1", "error_max": "155", "warn_min": "1", "warn_max": "95", "conversion": "0.02586", "normal_max_si": "4.01", "normal_max_us": "155", "normal_min_si": "1.55", "normal_min_us": "60", "units_si": "mmol/L", "units_us": "mg/dL" } ]

information

Interpretation:

From ATP III Guidelines.

LDL targets:

• “Very” high risk: guidelines suggest <70mg/dL may be a reasonable option, but data may suggest there is little incremental benefit to this extreme but with high associated cost.
• High risk: (known CAD, known other atherosclerotic disease, diabetes, etc): <100 mg/dL.
• Moderate risk: (>1 risk factor*): <130 mg/dL.
• Lower risk: (0-1 risk factors): <160 mg/dL.

From NCEP 2004 Guidelines.

*Risk factors include diabetes, cigarette smoking, HTN (BP 140/90 mm Hg or on antihypertensive medication), low HDL cholesterol (<40 mg/dL), and family history of premature CAD (CAD in male first-degree relative, or father <55 years, or female first-degree relative or mother <65 years).

refrences

{ "Clinical Practice Guidelines": [ { "href": "", "text": "" } ], "Manufacturer Website": [ { "href": "", "text": "" } ], "Original/Primary Reference": [ { "href": "https://www.nhlbi.nih.gov/health-pro/guidelines/current/cholesterol-guidelines/quick-desk-reference-html", "text": "NCEP 2004 update to LDL Guidelines" } ], "Other References": [ { "href": "https://www.ncbi.nlm.nih.gov/pubmed/15654445", "text": "Cordova CM, Schneider CR, Juttel ID, Cordova MM. Comparison of LDL-cholesterol direct measurement with the estimate using the Friedewald formula in a sample of 10,664 patients. Arq Bras Cardiol. 2004;83(6):482-7." } ], "Outcomes": [ { "href": "", "text": "" } ], "Validation": [ { "href": "", "text": "" } ], "Validations": [] }

pearls

• Remember, triglycerides should only be calculated when fasting.
• The Friedewald formula, on which this calculator is based, is known to be inaccurate at extremes of triglycerides and total cholesterol (Cordova 2004).

usecase

reasons

next_advice

Patients with elevated cholesterol may have success with diet and exercise, however those with other cardiovascular risk factors may require medication to reduce levels significantly.

LDL targets:

• “Very” high risk: guidelines suggest <70mg/dL may be a reasonable option, but data may suggest there is little incremental benefit to this extreme but with high associated cost.
• High risk: (known CAD, known other atherosclerotic disease, diabetes, etc): <100 mg/dL.
• Moderate risk: (>1 risk factor*): <130 mg/dL.
• Lower risk: (0-1 risk factors): <160 mg/dL.

From NCEP 2004 Guidelines.

*Risk factors include diabetes, cigarette smoking, HTN (BP 140/90 mm Hg or on antihypertensive medication), low HDL cholesterol (<40 mg/dL), and family history of premature CAD (CAD in male first-degree relative, or father <55 years, or female first-degree relative or mother <65 years).

next_actions

next_management

diseases

[ "Acute Coronary Syndrome", "Dyslipidemia", "Myocardial Infarction" ]

instructions

Note: the Friedewald formula is known to be inaccurate at extremely high triglyceride (>400 mg/dL) and total cholesterol levels. HDL cholesterol should not be higher than total cholesterol, review your entered values carefully.

If there is any question about accuracy of estimated LDL, a direct level should be measured.

published

2022-04-21T20:29:45.625Z

purpose

[ "Formula" ]

search_terms

[ "ACS", "cholesterol", "hdl", "triglycerides" ]

seo

{ "keywords_en": "LDL Calculated, LDL, HDL, triglycerides, ldl calc, ldl calculator, ldl calc online, ldl online, ldl, hdl, triglycerides calc, hdl calc, cholesterol calc, cholesterol average, low-density lipoprotein calc, low-density lipoprotein average, low-density lipoprotein calculator, low-density lipoprotein score, low-density lipoprotein scale, low-density lipoprotein issue, low-density lipoprotein cholesterol, bad cholesterol level, bad cholesterol calculator, bad cholesterol calculated, ldl based on hdl, ldl based on triglycerides, ldl from hdl, ldl from tryglycerides, ldl level, ldl risk, ldl risk factors, ldl smoking, ldl cigarettes, ldl DM, ldl diabetes, ldl htn, ldl hypertension, ldl high bp, ldl blood pressure, ldl family history, ldl hx, ldl family hx", "meta_description_en": "The LDL Calculated calculates LDL based on total and HDL cholesterol and triglycerides." }

specialty

[ "Cardiology", "Endocrinology", "Family Practice", "Hospitalist Medicine", "Internal Medicine", "Primary Care" ]

departments

[ "Cardiac", "Endocrine and Metabolic" ]

tags

[]

version_number

1

versions

[]

related

[ { "calcId": 38, "short_title_en": "Framingham Risk Score (Hard Coronary Heart Disease)", "slug": "framingham-risk-score-hard-coronary-heart-disease" }, { "calcId": 3398, "short_title_en": "2013 ASCVD Risk Calculator", "slug": "ascvd-atherosclerotic-cardiovascular-disease-2013-risk-calculator-aha-acc" }, { "calcId": 665, "short_title_en": "TIMI Risk Index", "slug": "timi-risk-index" } ]

ismed

false

section

[ "pearlsPitfallsViewed", "nextStepsViewed", "evidenceViewed" ]

cleaned_departments

[ "cardiology", "endocrine" ]

cleaned_use

[]

pub

true